Debra Granik on Down to the Bone:

The traditional storyline in an American film is usually in the form of a V shape. I am oversimplifying, but we see someone tumbling down, they hit bottom, and then they rise up again and find redemption. Anyone who personally, tangentially or culturally knows anything about addiction is aware that it resembles an EKG. Up and down, up and down. Very few people ever get clean on the first or second attempt. For many people, it’s something they have to try over and over again. You get knocked down and ask all the ethical questions like how many chances do you give a person? When is the last chance? How many chances do they get? Can you imagine how difficult it is to fit that in a feature-length film? But those are the questions that are worth asking...